Mitochondrial dysfunction in cholestatic liver diseases
نویسندگان
چکیده
منابع مشابه
Mitochondrial dysfunction in cholestatic liver diseases.
Cholestatic liver diseases are characterized by blockade of bile flow from the liver to the intestine, and accumulation of hydrophobic bile acids in the liver and plasma. As a consequence an inflammatory response evolves associated with increased apoptosis, oxidative stress, and eventually fibrosis. Cholestasis is associated with profound metabolic changes, alterations in the mitochondrial func...
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ژورنال
عنوان ژورنال: Frontiers in Bioscience
سال: 2012
ISSN: 1945-0494,1945-0508
DOI: 10.2741/e539